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The co-occurrence of high NRF2 target genes with low lipogenic genes was shared by some tissues but not all (Fig

Moreover, the current and lifetime prevalence of hepatic illness in bipolar disorder stands at 17 and 21%, respectively (42)

Several alternative therapeutic strategies have been investigated, including protein kinase C inhibitors [10], darbepoetin alfa [11], endothelin receptor antagonists (ERAs) [12], direct renin inhibitors [13], nuclear factor erythroid 2-related factor 2 activators [14], and combination of ACE inhibitor and ARB [15]

Its role in insulin sensitivity has made it a subject of particular interest for patients with metabolic conditions