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Mice exposed to chronic unpredictable mild stress (CUMS) for 6 weeks showed increased hypothalamic corticotropin-releasing hormone concentrations, elevated corticosterone levels and increased blood ammonia, which corresponded with anxiety-like behaviors, demonstrating HPA axis involvement in anxiety pathogenesis (Jia et al., 2024)

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In the Social Responsiveness Scale-Parent (SRS-parent) and Child Behaviour Checklist (CBCL), the study reported significant improvements in the core symptoms of ASD, with statistical significance in the SRS subscales

Eur J Biochem 220:645661 Dixon DP, Cole DJ, Edwards R (1998a) Purification, regulation and cloning of a glutathione transferase (GST) from maize resembling the auxin-inducible type-III GSTs