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Pharma regulations in China, India, Turkey, and elsewhere mean that Novos patent, and thus its monopoly, expires Saturday, and manufacturers are racing to produce low-cost versions

18 Therefore, G-site modification often guides the development of specific GST inhibitors

We were exploring ways of developing peptides that bind selectively, and we were very successful at that, but then we confronted the problem that our short, 23-residue peptides are not promising therapeutic candidates primarily because they cannot get into cells, Keating says

The trial product estimand evaluates the treatment effect for all randomised patients under the assumption that all patients remained on the trial product for the entire planned duration of the trial and did not use rescue medication