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45 [PMC free article: PMC12614067] [PubMed: 41224657] 343

The above applications reflect areas of preclinical research interest cited by ProHealth Longevity, not established human clinical outcomes

In summary, different GLP-1RAs improve skeletal muscle atrophy through multiple molecular mechanisms, involving multiple pathways such as insulin resistance regulation, inflammation suppression, and mitochondrial function improvement (see Table 1), providing a theoretical basis for the clinical treatment of sarcopenia with GLP-1RAs

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