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2002 Feb 7;346(6):393-403

The documented mechanisms are: VEGF stimulation in dermal fibroblasts that supports the microvascular network feeding the follicle, collagen and glycosaminoglycan synthesis at the follicular basement membrane, anti-inflammatory signaling that calms the chronic micro-inflammation associated with androgenetic alopecia, and direct follicular signaling that extends the anagen growth phase

Apply evenly to the face and gently massage or pat until fully absorbed AI-generated from the product information

That matters because blood-sugar control does the opposite: HbA1c is nearly maxed out by 10 mg, so the top dose is justified by weight, not by additional glucose lowering. Body size also shifts the felt dose

The aforementioned ROS-triggered strategies have also been employed to respond to high GSH levels within tumor tissues