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Incretins, such as GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), are secreted by entero-endocrine cells of the gastrointestinal tract to stimulate glucose-dependent insulin secretion and beta-cell proliferation

Additionally, tirzepatide has demonstrated significant enhancements in insulin sensitivity and beta-cell activity

This comprehensive review on Graves disease includes updates on disease aetiology and pathogenesis

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