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Given the essential role of SLC25A39 in mitochondrial glutathione transport, our results provide a mechanistic explanation for how SLC25A39 loss causes mitochondrial defects, neurodegeneration and anemia in yeast, flies and mice, respectively

While some may experience no side effects at all, others might find the first few weeks challenging

Pfizer halted development of its oral GLP-1 danuglipron in 2025 after a trial participant developed liver injury, reflecting safety concerns that require ongoing monitoring with real-world data

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These generic versions were often less expensive than brand-name medications, even though they contained the same active ingredient