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reducing hunger signals in the same powerful way, explained Gunter Kuhnle, a nutrition expert and food scientist at the UKs University of Reading, in an interview with the Daily Mail

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PMID: 18644225 Simon A, Emonard H, Hornebeck W, et al

The external 2-phenylpropionate moiety is stabilized by stacking with Y145 1.40b and hydrophobic interactions with L142 1.37b , while the carboxylic acid forms a salt bridge with K202 2.72b

Common overlapping side effects include gastrointestinal symptoms (nausea, vomiting, abdominal pain), increased heart rate and blood pressure, and excessive appetite suppression