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Injectable B12 bypasses absorption issues and is first-line treatment for malabsorption conditions, whilst oral doses of 1,0002,000 g daily may suit dietary deficiency without malabsorption

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Hepatocyte-specific Cdo1LKO abolished exercise-induced improvements in liver biochemistry with sustained high intrahepatic TG and TC, unaltered serum ALT/AST, and reduced basal metabolic rate, which confirms Cdo1 deficiency blocks exercise s hepatoprotective effects