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Some patients report that artificial sweeteners trigger nausea or alter taste perception, which is already affected in some semaglutide users

The drug is currently progressing through Phase 3 clinical development globally

Retatrutide belongs to a newer investigational category because it targets GLP-1, GIP, and glucagon receptors rather than only one or two pathways

The inclusion of benzyl alcohol (at 0.9%) imparts an antimicrobial effect by inhibiting bacterial growth and reproduction in the water

The GLP-1 agonist Semaglutide GLP-1 increases insulin release, lowers glucagon release, delays gastric emptying, and reduces appetite