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Rodent, goat, and petri-dish results establish biological plausibility and guide further research, but they routinely fail to translate to humans

Newsome DA, Swartz M, Leone NC, Elston RC, Miller E

Moreover, genetic modulation of this receptor highlights its critical role in neural function: deletion of GLP-1R markedly impairs cognitive performance, while its overexpression enhances cognitive abilities in murine models (173)

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