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GPX4 is an essential regulator of ferroptosis, facilitating the detoxification of cellular lipid peroxidation using glutathione as a cofactor [265]

In most people, both of them can convert into each other

L-carnitine is a carrier of active acetyl and acyl groups (Figure 1) ( 2.3 Detoxification of potentially toxic metabolites A critical function of L-carnitine involves the detoxification of potentially toxic metabolites generated during intermediary metabolism, particularly those associated with impaired fatty acid -oxidation

This accumulation activates the innate immune response via NLRP3 inflammasome-mediated IL-1 production, further propagating inflammation

View Full Study Binding Domain Characterization of Growth Hormone Secretagogue Receptor