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It can place additional stress on the joints, make physical activity more difficult, and increase the risk of chronic conditions such as type 2 diabetes, high blood pressure, and heart disease
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GIP is an incretin hormone secreted by K-cells in the proximal small intestine in response to fat and carbohydrate ingestion
Berberine, an isoquinoline alkaloid from Berberis spp., has demonstrated promising antioxidant activity via promoting heme oxygenase-1 (HO-1) expression, activating Nrf2/AMPK/SIRT1 signaling, inhibiting the NLRP3 inflammasome, balancing glutathione levels, and regulating mitochondrial redox processes (Sunhe et al., 2024
