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While not yet proven in formal trials, the mechanistic rationale and early clinical evidence suggest these medications may offer the first real opportunity to medically manage lipedemas underlying pathophysiology

For some patients, staying on GLP-1 medications long-term may be necessary, especially if there are underlying medical conditions like Type 2 diabetes

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IGlarLixi is a fixed-ratio combination of insulin glargine and lixisenatide, containing 100 U/mL of glargine and 33 lg/mL of lixisenatide in a 3-mL prefilled injection pen