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Similar content being viewed by others Introduction The intervertebral disc (IVD) arises from the embryonic notochord and mesenchyme and develops into a complex tissue that permits movement between vertebrae and provides flexibility and integrity to the spine [1]

Single agent growth-inhibitory effects have been reported in breast, colon, and meningioma tumor xenografts, which suggests that GHR antagonism as a monotherapy may have efficacy in some tumor types

Exercise can also help stimulate healthy bowels and prevent slow motility

In rat models, BPC-157 significantly improved healing of transected Achilles tendons and medial collateral ligaments, supporting its role in soft tissue regeneration. Chang et al., Journal of Orthopaedic Research 4

Metabolomics data are provided in the Supplementary Tables 3, 4