This accumulation facilitates the binding of -catenin to TCF7L12, triggering the activation of genes associated with osteogenesis
Side effects are minimal
Serious Warning Signs Severe abdominal pain: Especially if sudden onset, radiating to back, or with vomiting (possible pancreatitis, occurred in 0.3% of patients) Severe vomiting: If unable to keep any fluids down for 24 hours (dehydration risk) Signs of dehydration: Dark urine, dizziness on standing, confusion, decreased urination (acute kidney injury risk) Vision changes: Blurred vision, eye pain (rare but requires evaluation) Rapid heart rate: Persistent heart rate over 100 at rest (some increase normal, average 2-4 bpm, but sustained tachycardia needs evaluation) Suicidal thoughts: Any thoughts of self-harm (under 1% occurrence but requires immediate support) Severe allergic reaction: Difficulty breathing, throat swelling, severe rash (anaphylaxis requires emergency care) Lump in neck: Especially with difficulty swallowing (thyroid concern, rare but part of class warning) Trust your instincts

Martin trained at the University of California, Irvine Hospital in family medicine, where he treated patients of all ages with obesity, diabetes, thyroid & hormone disorders, high blood pressure, age-related diseases, chronic pain, and autoimmune conditions
Its important to understand the potential side effects of each medication to make an informed decision with your healthcare provider