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Tesofensine Tesofensine is a triple monoamine reuptake inhibitor (serotonin, norepinephrine, dopamine) that increases energy expenditure and enhances fat oxidation

GLP-1RAs commonly cause gastrointestinal side effects that are dose-dependent and typically settle once the dose stabilizes

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Nevertheless, translating these experimental technologies into safe, effective, and commercially viable products requires extensive clinical trials to establish pharmacokinetics, bioavailability, efficacy, and safety profiles