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J Colloid Interface Sci 361:270277

The selected patients with single thyroid nodules ranging from 2 to 5 cm were followed up over 12 weeks, which comprised 3 visits, 6 weeks apart from each other

Based on analyses of available crystal structures a tentative model for 23 (HA08) binding to IRAP was created in 2016 by applying MD simulations and calculating associated binding free energies by the linear interaction energy (LIE) method