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Web Link In humans, the initial symptoms are nausea, fatigue, and diarrhea

The alpha-melanocyte-stimulating hormone (-MSH) gene is an alternatively spliced gene originating from the same host gene that harbors ACTH

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As cells age, mitochondria can become less efficient, leading to a decline in overall cellular function

Dysregulated histone acetylation is increasingly linked to tumor progression and therapeutic resistance, where acetylation-driven activation of survival and redox pathways fosters drug toleranceincluding reduced sensitivity to AR-directed therapies in CRPC [25,26,27,28]