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If you have certain digestive disorders, including pernicious anemia, or have had gastric bypass surgery, oral B12 will simply not work because you can't absorb it correctly

GLP-1s, however, may also exert direct hormonal effects as GLP-1 receptors can be found across the hypothalamus-pituitary-ovarian (HPO) axis and influence gonadotropin release and follicle development

With too rapid weight loss or failure to build or maintain muscle mass, you could actually become weaker with muscle loss

Journal of Practical Diabetology 2008;4:50-51

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