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Vitamin B12 is essential for the health and development of a fetus

B12:A vitamin that dissolves in water and is actively engaged in the metabolic process, aiding the body in utilizing fats and carbohydrates as an energy source and facilitating the synthesis of new proteins

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Additionally, chronic conditions such as HIV and tuberculosis have been implicated in B12 deficiency due to increased metabolic demand and altered absorption mechanisms ( The diagnosis of vitamin B12 deficiency typically relies on low total B12 levels and elevated concentrations of homocysteine (Hcy), as well as levels of transcobalamin-bound B12 (holoTC) and methylmalonic acid (MMA), which serve as functional indicators of cobalamin insufficiency ( Vitamin B12 requirements fluctuate throughout the life course, influenced by metabolic demand and physiological changes