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Both human 5 -reductase-2 and 5 -reductase-1 genes have 5 exons and 4 introns, and encode a highly hydrophobic 254 and 259 amino acid protein with a molecular weight of approximately 28.4 and 29.5 kilodaltons, respectively

It consists of three amino acids: cysteine, glutamine, and glycine

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Medications such as Ozempic, Mounjaro, Wegovy, and Rybelsus have been associated with major adverse effects, such as severe abdominal discomfort, gastroparesis (stomach paralysis), and pancreatic problems

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