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Before the promising therapeutic impact of miRNA can be realized, there are several challenges to be addressed, which include but not limited to targeted delivery of oligonucleotides to specific organs, tissues and cell types, poor bioavailability, limited tissue permeability (Stylianopoulos and Jain, 2013), potential drug resistance, and instability (Raemdonck et al., 2008)

Combination treatment of RIF and L-GSH enhances standard RIF treatment by producing smaller and minimal granulomas, which can improve lung function by reducing the risk of permanent lung damage from M

Any accumulation of AGE is associated with various diseases, such as diabetes mellitus type 2, metabolic syndrome, cardiovascular diseases, ovarian aging, neurodegenerative disorders, obesity and PCOS [33, 34, 35]

Methods We searched four electronic databases (PubMed, Scopus, Web of Science, and Cochrane CENTRAL Register of Controlled Trials)

& Pruniaux, M