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The SUSTAIN 6 trial found that once-weekly subcutaneous semaglutide reduced the risk of MACE by 26% compared to placebo over a 2-year period

From concentration response curves (Supplemental Figures 5-8), pIC 50 values, and transduction ratios (log c /K A, where receptor expression was also taken into account) that quantify signalling efficiency, were calculated

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Rosenstock J, Seman LJ, Jelaska A, Hantel S, Pinnetti S, Hach T, et al

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