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They may be particularly suitable for subjects at a higher risk of low blood glucose, such as the elderly, or for those who prefer treatments that minimize weight gain or involve oral medications

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If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)

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Facilities administering the survey themselves can follow-up with all eligible patients throughout the 65-day response window based on the procedure date, rather than the survey administration date