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Safety screening: Before administering high-dose vitamin C, we screen for contraindications including G6PD deficiency, kidney disease, and other conditions that require modified protocols

This work now shows a direct line from biochemical and biophysical understanding of protein interactions to an inhibitor, says Kritzer, who was not involved in the research

Jefferson J Psychiatry 4 (1), 6 (1986)

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Despite great advances in the mechanistic understanding of inherited channelopathies, translation of mechanism-based novel therapies into clinical use remains challenging due to problems in designing and funding clinical studies with sufficient power in these rare diseases, particularly for second use applications of already approved drugs