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2021;42(Supplement_1):ehab724.0513

With DSIP being largely relegated to laboratory use, theres currently no standard protocol for its use among humans

Continuous medical check-ups are necessary to monitor for manage any long-term risks

Metreleptin is a once daily subcutaneously administered leptin analogue approved by the FDA in 2014 for use in people with leptin deficiency or congenital/acquired lipodystrophy, with good clinical results in these conditions [86]

Winfrey has been discrete about the kind of medication she used in her weight loss journey, revealing only that she relied on it "as a tool to manage not yo-yoing." Winfrey has also been candid about the stigma surrounding using certain medications for weight loss