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Patients entered a run-in treatment period on glimepiride (greater than or equal to 4 mg per day) alone or glimepiride in combination with metformin (greater than or equal to 1500 mg per day)

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The drugmaker stated that Orforgliprons positive Phase 3 ATTAIN-1 trial results have put it on track to submit to global regulatory agencies by the end of 2025

The dose volume was calculated for individual animals on the first day of treatment and was re-calculated according to the most recent body weights recorded during the treatment period

Flavin oxidase-induced ROS generation modulates PKC biphasic effect of resveratrol on endothelial cell survival