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doi: 10.2337/diab.42.5.658 95 ReedJBainSKanamarlapudiV

GLP-1 was discovered in 1983 when Bell et al

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(Compare that to semaglutide and tirzepatide , which result in 13.7 percent and about 20 percent body weight reductions after 72 weeks, respectively.) Weve never seen weight loss at this level before, says Ania Jastreboff, MD, PhD , the director of the Yale Obesity Research Center at the Yale School of Medicine, who has been involved in research on the drug

But still, less than one in five large employers covers these drugs for weight loss, she said