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We also used MetaboAnalyst v5.0 (Xia Lab @ McGill University, Montreal, QC, Canada) [30] to identify the metabolites that contribute to group separation using Partial Least Squares-Discriminant Analysis (PLS-DA), heat map, and pathway analysis

Tenomodulin is highly expressed in adipose tissue, increased in obesity, and down-regulated during diet-induced weight loss

Kramer HJ, Choi HK, Atkinson K, Stampfer M, Curhan GC

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