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In patients with lower back pain, the efficacy of flupirtine was comparative with that of tramadol and superior to placebo, whilst the incident of treatment-emergent adverse effects and related study discontinuations was significantly lower in the flupirtine group relative to the tramadol group

Drop back to a lower dose if symptoms occur

Dietary Habits: Vegetarians, vegans, and individuals with restrictive diets may need regular B12 injections to maintain optimal levels

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When levels drop, the body becomes less efficient at repairing damage and clearing out metabolic waste