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Taken together, these results may be indicative of elevated energy expenditure, which could partly be explained by the alteration in pathways through which fat is metabolized

Because L-Citrulline largely bypasses first-pass liver metabolism (where some L-Arginine is broken down before reaching the bloodstream), research suggests that L-Citrulline may raise plasma L-Arginine levels more efficiently, gram for gram, than supplementing L-Arginine directly