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Potential Long-Term Risks Although AOD-9604 does not increase IGF-1 levels, there are concerns about its long-term metabolic effects, including: Unknown impact on fat metabolism regulation Since AOD-9604 alters fat-burning pathways, researchers are still investigating whether prolonged use could affect natural fat metabolism

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Plant Pathol 14:9296

To further test this possibility, we performed a cluster analysis of RNA-seq data from 25 liver cancer cell lines derived from human liver tumors in the Broad Institute Cancer Cell Line Encyclopedia (CCLE) database