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Wheeler MB, Lu M, Dillon JS, Leng XH, Chen C, and Boyd AE, 3rd

The number of patients at the 4-milligram dose who discontinued treatment due to side effects was lower than the placebo group, which Skovronsky called "remarkable to see." Around 4% of patients on that dose stopped the drug due to side effects, compared with nearly 5% with the placebo

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The headline result: participants on the 12mg dose lost an average of 28.7% of their body weight, which works out to approximately 71 lb for someone starting around 248 lb