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The addition of glucagon receptor agonism is particularly notable: preclinical evidence and early human data suggest it may increase energy expenditure and promote fat breakdown (lipolysis), potentially offering greater weight reduction than dual agonists alone though the precise contribution of each receptor in humans remains an active area of research
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Emerging reviews of the GLP-1 market anticipate continued demand, pipeline diversification, and health-system impact as agents move earlier in care pathways, reinforcing the case for meaningful market expansion through 2026-2028
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