Not specific to IGF-1 LR3 but pathway-relevant
Competing interests DB received presentation fees (TEVA, Novartis and Pfizer), travel fees (Allergan, TEVA, Pfizer, Abbvie and Lundbeck), advisory board fees (Novartis, Lilly, Teva, Lundbeck, Pfizer and Abbvie) and participated in clinical trials (TEVA, Lundbeck, Novartis, Lilly and Novo Nordisk Foundation) outside of the submitted work
Immunofluorescence confocal laser microscopy 1.10 5 cells were cultured at 37 C in 5% CO 2 for 48 h in a polystyrene vessel chamber on tissue culture treated glass slide (BD Falcon)
Arginine and arginine-dependent polyamine production are important not only for biomass synthesis, which supports tumor aggressiveness, but also as regulators in immunometabolism (Mondanelli et al., 2017), which represents an important target for effective cancer immunotherapy
Stability Considerations for Lyophilized Peptide Pharmaceuticals: Storage Conditions and Reconstitution Protocols