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PMID 27630114

Cons: High cost, possible side effects, dependency for sustained results

(GLP-1 agonists appear to be helpful in a wide variety of inflammatory diseases and have been found to effect multiple immune pathways including tumor necrosis factor alpha (TNF-) and nuclear factor kappa beta (NF-) inhibition and NLRP3 inflammasome and IL-1B suppression.) While he doesnt have proof of it, he believes the inflammation reduction is allowing the immune system to recover and keep the infections under control

The decrease in body weight in the groups given sitagliptin in combination with metformin was similar to that in the groups given metformin alone or placebo