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10.1038/s41467-020-14934-5 87 WuZ.HuangZ.SunL.FuY.ChenS.WuS.et al (2024)

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That short activity window is part of why once-daily dosing is often used in educational referencesone consistent daily pulse can be enough to support a physiologic-style rhythm, especially when paired with steady sleep timing and nutrition consistency (since sleep, meal timing, and training load can all influence GH signaling day to day)