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Risk of bias in individual studies and the quality of meta-analysis In order to assess the quality of studies, the Cochrane Collaboration tool for risk of bias was used 16

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Moreover, Syn-S129p triggers protein-protein interactions by inducing conformational changes within the C-terminal region, which are essential for mediating Syn function at the synapse and within the nucleus 71,73,89

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Adverse Effects: Gastrointestinal side effects and potential long-term implications require careful assessment