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The receptor, coupled to a G protein, stimulates adenylate cyclase, which converts ATP into cyclic AMP (cAMP)

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PapadopoulouLCSueCMDavidsonMMTanjiKNishinoISadlockJEet al

For instance, research comparing individuals using GLP-1 RAs to those who aren't has suggested a benefit beyond their primary use for diabetes and obesity [0fde]