These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication
Methods Selection of studies for review The inclusion criteria for studies were defined as: (a) participants diagnosed with an autism spectrum disorder using standardised criteria such as the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV-R [51] or the Childhood Autism Rating Scale (CARS) scores [52]
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This method stabilises the peptide, preventing degradation and ensuring its bioactivity remains intact until it is reconstituted for use.
Oral supplements typically take 4-8 weeks of consistent use to show noticeable effects, with optimal results around 3-4 months