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Moreover, these drugs may also alter the gut microbiome the diverse ecosystem of bacteria that plays a crucial role not just in digestion, but in immunity, inflammation, and even mental health

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doi: 10.1073/pnas.95.1.322 163 MickelsenLEFlynnWFSpringerKWilsonLBeltramiEJBolisettyMet al

The role of oxidative stress and antioxidants in liver diseases

Between 65% and 96% of participants taking orforglipron achieved an A1C level below 7.0% at 26 weeks.174 Currently, Eli Lilly has initiated a Phase III development program to further investigate the efficacy and safety of orforglipron in treating obesity, overweight, and T2DM