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The thiamine-induced increases in contractions of the intestine smooth muscle and peristalsis, observed in a number of independent in vitro experiments on muscle strips of gastrointestinal tract (207, 219222), support the action of thiamine on ACh signaling in ENS in the absence of central regulation (236)

Fecal Metals Folate MetabolismThe test analyzes the levels of the primary forms of folate in plasma to evaluate folate metabolism and cellular methylation processes

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Flexibility matters, especially as the science evolves and new treatment options become available

The Interchangeability Hurdle The interchangeability designation is critical to understanding biosimilar market dynamics