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The immunohistochemical results showed that the expression of GLP-1R was down-regulated and the expression of STING, ACSL4 and TNF- was up-regulated in the RA group compared to the NC group

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Interestingly, duplication of NSD1 results in microcephaly in 74% of 5q35 syndrome cases, along with growth restriction and developmental delay in nearly 90% of affected individuals (Quintero-Rivera et al., 2021)

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