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Based on the results shown in the present manuscript, we can suggest that the follow-up of a HAD with pertinent adaptations could be used as a therapeutic aid to improve the balance of antioxidants and oxygen/nitrogen reactive species to the antioxidant side, where oxidative stress conditions persist

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BMI, blood-pressure, and weight-management records support the request

Missing doses disrupts the escalation schedule and potentially resets tolerance, requiring a step back to lower doses

Based on these findings, altered metabolism of carnitine/acylcarnitine was observed in AHU, especially in patients with gout who have more changed carnitine/acylcarnitine