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MOTS-c is administered via subcutaneous or intramuscular injection, typically 3-7 times per week depending on individual goals and response

4 By reducing the inflammatory load and metabolic stress that perpetuates HS lesions, GLP-1 RAs may interrupt the cycle of flare and progression that characterizes the disease

Drinking can cause blood sugar to spike from sugary mixers, then drop lower than normal hours later as the liver prioritizes clearing alcohol over releasing glucose

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In Ania Jastreboff's SURMOUNT-1 trial, published in the NEJM in 2022, mean weight loss was about 15.0% on 5 mg, 19.5% on 10 mg, and 20.9% on the 15 mg dose over 72 weeks