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doi: 10.1007/s10549-009-0415-0 317 WangYZhaoYChongFSongMSunQLiTet al

33,34 In an eight day, open-label study of palliative care patients with incurable cancer, flupirtine at 100 to 300 mg, four times daily, reduced pain scores and was associated with some reduction in opioid use