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Direct projections of MCs from the OB to the arcuate nucleus also exist 40 and food odours can rapidly inhibit AgRP neurons and excite POMC neurons 41,42

From a clinical perspective, it is relevant to address gut microbiome composition as this is a foundational component of human physiology

Lipo B12 injections are a combination of vitamin B12 and lipotropic compounds like Methionine, Inositol, and Choline (often called MIC)

If it's lasted more than a few weeks, rule out thyroid issues, anaemia, or B12 and vitamin D gaps first all far more common in India

Since these micro-traumas are often more common in lower limbs and joints, these areas are more common sites for a gout attack