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Most GLP-1R agonists have gastrointestinal side effects, including nausea, vomiting, diarrhea and constipation, which may be more pronounced in elderly patients with AD and affect treatment compliance
JAMA Surgery
The FDA added semaglutide to its official drug shortage list
Among injectables, Roche's CT-388 (enicepatide) showed 22.5% weight loss in Phase 2 at 48 weeks with no plateau reached, and Amgen's MariTide reached 20% at 52 weeks in Phase 2
Telogen effluvium from rapid metabolic shifts The most common cause of GLP-1 related hair loss is telogen effluvium, a condition where a large percentage of hair follicles simultaneously shift from the anagen (growth) phase to the telogen (resting) phase
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