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Melatonin suppresses the Warburg effect by down-regulating glucose uptake and lactate production, which is essential for the survival of the HCC cells [96]

Finally, the study was conducted at a single center with a relatively homogeneous sample, limiting the generalizability of the results to other populations

Researchers should distinguish between chemical stability, experimental suitability, and biological interpretation

Expert Review of Neurotherapeutics 2010

On the other hand, excessive intake of certain nutrients, such as iron and copper, can increase oxidative stress and disrupt metal homeostasis, leading to tissue damage and impaired detoxification